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Characterising populations living close to intensive farming and composting facilities in England
《环境科学与工程前沿(英文)》 2021年 第15卷 第3期 doi: 10.1007/s11783-020-1332-z
• Bioaerosol emitted from farming and composting facilities may pose health risks.
关键词: Composting Intensive farming Bioaerosol Population characteristics Public health
null
《医学前沿(英文)》 2015年 第9卷 第4期 页码 468-477 doi: 10.1007/s11684-015-0419-6
Mature T-cell lymphoid malignancies comprise a group of heterogeneous diseases that vary in clinicopathological features, biological behavior, treatment response, and prognosis. Bone marrow (BM) infiltration is more commonly present in mature T-cell lymphoid malignancies compared with their B-cell counterparts and hence important for differential diagnosis. In this study, clinical characteristics and prognostic factors were analyzed in 225 patients with mature T-cell lymphoid malignancies treated in a single institution. These included 29 cases of T-cell lymphoproliferative disorders (T-LPD, all with BM infiltration) and 196 cases of T-/natural-killer-cell lymphoma (T/NKCL, 56 with BM infiltration and 140 without BM infiltration). The estimated 5-year overall survival (OS) rates of T-LPD and T/NKCL were 96.6% and 37.3%, respectively. T-LPD patients were less likely to exhibit poor performance status, advanced disease stage, presence of B symptoms, or abnormal level of serum β-2 microglobulin. With similar pathological characteristics, T/NKCL patients with BM infiltration showed significantly lower response rates and shorter OS than those without BM infiltration (P = 0.0264 and P<0.0001, respectively). Multivariate analysis indicated that poor performance status, advanced disease stage, elevated serum lactate dehydrogenase level, and BM involvement were independent unfavorable prognostic factors. The Glasgow Prognostic Score may be more efficient than the International Prognostic Index in predicting disease outcome in T/NKCL. In conclusion, clinical characteristics may be useful in more effectively stratifying patients with mature T-cell lymphoid malignancies.
关键词: mature T-cell lymphoid malignancies clonal T-cell population bone marrow infiltration prognostic factors
Simulation of bubble column reactors using CFD coupled with a population balance model
Tiefeng WANG
《化学科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 162-172 doi: 10.1007/s11705-009-0267-5
关键词: bubble column computational fluid dynamics bubble breakup and coalescence population balance model bubble size distribution
Hongyan LI, Yu ZHANG, Min YANG, Yoichi KAMAGATA
《环境科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 43-48 doi: 10.1007/s11783-012-0397-8
关键词: ammonia-oxidizing bacteria hydraulic retention time nitrification activity nitrite-oxidizing bacteria population dynamics
Socialized care services for the aged population: System construction and support measures
《工程管理前沿(英文)》 2023年 第10卷 第2期 页码 339-353 doi: 10.1007/s42524-022-0208-2
关键词: socialized care service for the elderly system construction support measure
null
《医学前沿(英文)》 2012年 第6卷 第3期 页码 322-328 doi: 10.1007/s11684-012-0204-8
The aim of this study was to determine the prevalence of overweight and obese subjects in the Shanghai population of China and its association with undiagnosed hypertension, by taking age, gender and place of residence (urban or suburban) into account. A cross-sectional population-based survey was conducted in 2007. The sample included 13 359 participants aged 15–69 years. Weight, height, and blood pressure were recorded, and information about gender, age and place of residence was obtained. Overweight and obesity prevalence were calculated by the body mass index (BMI) definition recommended by Working Group on Obesity in China (normal weight, 18.5–23.9 kg/m2; overweight, 24–27.9 kg/m2; obesity,≥28 kg/m2). Undiagnosed hypertension was defined by China criteria in accord with that of WHO-ISH (subjects with systolic pressure≥140 mmHg, and/or diastolic pressure≥90 mmHg). Multiple logistic regression analyses were used to assess the association of overweight or obesity with undiagnosed hypertension by adjusting for age, gender and place of residence. The overall overweight, obesity, and undiagnosed hypertension prevalence were 27.6% (95% CI: 26.8–28.4), 6.6% (95% CI: 6.2–7.0), and 15.5% (95% CI: 14.9–16.1), respectively. Compared to normal weight subjects, the odds ratios (OR) for subjects who were overweight and had hypertension was 2.33 (95% CI: 2.10–2.59); that for obesity and hypertension was 4.27 (95% CI: 3.66–4.99). These data suggest that overweight and obesity prevalence and their association with undiagnosed hypertension are high in our study population.
关键词: overweight obesity undiagnosed hypertension prevalence association
Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era
null
《医学前沿(英文)》 2012年 第6卷 第2期 页码 204-211 doi: 10.1007/s11684-012-0202-x
We evaluated the outcomes of chronic myeloid leukemia (CML) patients in three clinical phases, namely, chronic (CP), accelerated (AP), and blast (BP) phases, receiving imatinib treatment. The single-institution treatment experiences of Chinese patients with CML were presented. A total of 275 CML patients (CP, 210; AP, 24; and BP, 41) who received imatinib between February 2001 and April 2008 were enrolled in this study. We evaluated the responses (hematologic, cytogenetic, and molecular), overall survival (OS), treatment event-free survival (EFS), and prognostic factors of outcome. At the cut-off point, the complete cytogenetic response (CCyR) and complete molecular response rates of patients in the CP were 84.7% and 61.9%, respectively, which were significantly higher than those of patients in the AP (50% and 29.1%, respectively, both P<0.001) and BP (24.3% and 9.7%, respectively, both P<0.001). The estimated five-year OS and five-year EFS rates were 93.2% and 86.4% for CP patients, as well as 64.5% and 50.9% for AP patients, which were significantly higher than those for BP patients (P<0.001). In CP patients, univariate analysis revealed that early treatment with imatinib, achieving CCyR within 12 months, additional cytogenetic abnormalities, and kinase domain mutations were associated with the treatment outcome. More patients are needed to carry out multivariate analysis.
关键词: imatinib chronic myeloid leukemia complete cytogenetic response
Projections of heat-related excess mortality in China due to climate change, population and aging
《环境科学与工程前沿(英文)》 2023年 第17卷 第11期 doi: 10.1007/s11783-023-1732-y
● Four scenarios were used to project heat-related excess mortality in China.
Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern
null
《医学前沿(英文)》 2014年 第8卷 第1期 页码 113-117 doi: 10.1007/s11684-014-0310-x
Papillary thyroid carcinoma (PTC) is one of the most common tumors of the thyroid gland. The common risk factors of PTC include ionizing radiation, positive family history, and thyroid nodular disease. PTC was identified in Europeans by conducting a genome-wide association study, and a strong association signal with PTC was observed in rs944289 and NKX2-1 (located at the 14q13.3 locus), which was probably the genetic risk factor of PTC. This study aimed to examine the association of this gene with PTC in Chinese. A total of 354 patients with PTC and 360 healthy control subjects from the Han population of Northern China were recruited in the study. These individuals were genotyped to determine rs12589672, rs12894724, rs2076751, and rs944289. The association of rs944289 with PTC was obtained (C vs. T, P=0.027, OR=1.264, 95% CI=1.026-1.557; and C/C-C/T vs. T/T, P=0.034, OR=1.474, 95% CI=1.028-2.112). Conducting a subgroup analysis, we found a marginal difference in the allele frequency distribution of rs944289 (adjusted P=0.062) between the patients with PTC and multi-nodular goiter and the control subjects. We also observed an interaction (P=0.029; OR=2.578, 95% CI=1.104-6.023) between rs944289 and diabetes in patients with PTC. In conclusion, rs944289 was associated with an increased risk of PTC in the Han population of Northern China, but no clear association was observed in either of the tag single nucleotide polymorphisms of NKX2-1.
关键词:
Genetic diversity and population structure of indigenous chicken breeds in South China
Xunhe HUANG,Jinfeng ZHANG,Danlin HE,Xiquan ZHANG,Fusheng ZHONG,Weina LI,Qingmei ZHENG,Jiebo CHEN,Bingwang DU
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 97-101 doi: 10.15302/J-FASE-2016102
关键词: microsatellites genetic diversity population structure indigenous chicken South China conservation
《医学前沿(英文)》 2021年 第15卷 第6期 页码 903-912 doi: 10.1007/s11684-021-0871-4
关键词: homocysteine hyperhomocysteinemia H-type hypertension Chinese
《环境科学与工程前沿(英文)》 2022年 第16卷 第8期 doi: 10.1007/s11783-022-1522-y
• Simultaneous C & N removal in Methammox occurs at wide C:N ratio.
关键词: Methanogens Biological Nitrogen Removal (BNR) Simultaneous Methammox C:N ratio
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
《环境科学与工程前沿(英文)》 2011年 第5卷 第1期 页码 48-56 doi: 10.1007/s11783-011-0305-7
关键词: ammonium-rich wastewater membrane biofilm reactor nitrification redox stratification shortcut nitrogen removal
《环境科学与工程前沿(英文)》 2022年 第16卷 第9期 doi: 10.1007/s11783-022-1552-5
• The airborne bacteria of Mexico City are representative of urban environments.
关键词: Airborne bacteria Urbanisation PM10 Mexico City Microbiome
Genetic variability of Appaloosa horses: a study of a closed breeding population from Argentina
Claudia Malena CORBI-BOTTO,Sebastian Andres SADABA,Elina Ines FRANCISCO,Paula Belen KALEMKERIAN,Juan Pedro LIRON,Egle Etel VILLEGAS-CASTAGNASSO,Guillermo GIOVAMBATTISTA,Pilar PERAL-GARCIA,Silvina DIAZ
《农业科学与工程前沿(英文)》 2014年 第1卷 第3期 页码 175-178 doi: 10.15302/J-FASE-2014019
关键词: horse genetic diversity microsatellite Appaloosa population structure conservation
标题 作者 时间 类型 操作
Characterising populations living close to intensive farming and composting facilities in England
期刊论文
Clinical characteristics and prognostic factors of patients with mature T-cell lymphoid malignancies:
null
期刊论文
Simulation of bubble column reactors using CFD coupled with a population balance model
Tiefeng WANG
期刊论文
Effects of hydraulic retention time on nitrification activities and population dynamics of a conventional
Hongyan LI, Yu ZHANG, Min YANG, Yoichi KAMAGATA
期刊论文
Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population, China: a cross-sectional population-based survey
null
期刊论文
Projections of heat-related excess mortality in China due to climate change, population and aging
期刊论文
Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern
null
期刊论文
Genetic diversity and population structure of indigenous chicken breeds in South China
Xunhe HUANG,Jinfeng ZHANG,Danlin HE,Xiquan ZHANG,Fusheng ZHONG,Weina LI,Qingmei ZHENG,Jiebo CHEN,Bingwang DU
期刊论文
Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening
期刊论文
Enhancing the efficiency of nitrogen removing bacterial population to a wide range of C:N ratio (1.5:
期刊论文
Nitrifying population dynamics in a redox stratified membrane biofilm reactor (RSMBR) for treating ammonium-rich
Rongchang WANG, Xinmin ZHAN, Yalei ZHANG, Jianfu ZHAO
期刊论文
bacteria associated with particulate matter from a highly urbanised metropolis: A potential risk to the population
期刊论文
Genetic variability of Appaloosa horses: a study of a closed breeding population from Argentina
Claudia Malena CORBI-BOTTO,Sebastian Andres SADABA,Elina Ines FRANCISCO,Paula Belen KALEMKERIAN,Juan Pedro LIRON,Egle Etel VILLEGAS-CASTAGNASSO,Guillermo GIOVAMBATTISTA,Pilar PERAL-GARCIA,Silvina DIAZ
期刊论文